DYSPEPSIA MANAGEMENT The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies
نویسندگان
چکیده
Dyspepsia is a common condition in the general population but data are lacking on the benefits of effective acid inhibition with proton pump inhibitors in functional dyspepsia. The results of the large, randomised, double blind clinical trials, BOND and OPERA, the Scandinavian PILOT study, and a follow up study, ENCORE, are reviewed. BOND, OPERA, and PILOT aimed to address the question of whether effective acid inhibition with the proton pump inhibitor omeprazole relieves symptoms in patients with functional dyspepsia. ENCORE followed on from this, addressing the consequences of relieving symptoms in patients with functional dyspepsia once they are off therapy.
منابع مشابه
The potential role of acid suppression in functional dyspepsia: the BOND, OPERA, PILOT, and ENCORE studies.
Dyspepsia is a common condition in the general population but data are lacking on the benefits of effective acid inhibition with proton pump inhibitors in functional dyspepsia. The results of the large, randomised, double blind clinical trials, BOND and OPERA, the Scandinavian PILOT study, and a follow up study, ENCORE, are reviewed. BOND, OPERA, and PILOT aimed to address the question of wheth...
متن کاملThe effectiveness of cognitive behavior stress management on functional dyspepsia symptoms
Introduction: Functional dyspepsia and digestive disorders arecommon, debilitating and costly. Little information is availableabout the role of stress management in terms of cognitivebehavioraltreatment of dyspepsia. The purpose of this studywas to investigate the effectiveness of cognitive-behavioral stressmanagement on functional dyspepsia symptoms in patients whoreferred to digestion clinics...
متن کاملPsychological factors in patients with peptic ulcer and functional dyspepsia
Abstract Background: The role of psychological factors in peptic ulcer disease (PUD) and functional dyspepsia (FD) has not been clearly determined. In this study the role of conflict management styles, psychiatric symptoms, and alexithymia were assessed in patients with PUD and FD and in the healthy individuals. Methods: Ninety subjects [30PUD (15 women, 15 men), 30 FD (15 women, 15 men), and...
متن کاملEffects of Ocimum Basilicum on Functional Dyspepsia: a Double-Blind Placebo-Controlled Study
Background: Traditionally some people employ Ocimum basilicum (Shaspram) to relieve the symptoms of dyspepsia. We therefore studied the effects of oral extract of this medicinal plant on functional dyspepsia. Methods: In a double-blind placebo-controlled clinical trial, the effect of a four-week treatment of Shaspram was evaluated on functional dyspepsia. Two hundred cases from all patients ref...
متن کاملSerum Selenium Level in Patients with Gastric Non-Cardia Cancer and Functional Dyspepsia
Background: Gastric cancer (GC) is the most common gastrointestinal cancer in Iran. Helicobacter pylori (H. pylori) accounts as one of the main risk factors for gastric non-cardia cancer (GNCC). It is suggested that high serum selenium level may have a protective role in GNCC. In this cross-sectional study, we determined the serum Se level and the status of H. pylori infection in two population...
متن کامل